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Kazuya Fukumura Selected Research

naldemedine

6/2020Clinical Drug-Drug Interaction Studies to Evaluate the Effects of a P-Glycoprotein Inhibitor, CYP3A Inhibitors, and a CYP3A Inducer on the Pharmacokinetics of Naldemedine in Healthy Subjects.
1/2020The Influence of Renal or Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Naldemedine.
9/2019Absorption, distribution, metabolism, and excretion of radiolabeled naldemedine in healthy subjects.
10/2018Population Pharmacokinetics and Exposure-Response Relationships of Naldemedine.
1/2018Phase 1, Randomized, Double-Blind, Placebo-Controlled Studies on the Safety, Tolerability, and Pharmacokinetics of Naldemedine in Healthy Volunteers.

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Kazuya Fukumura Research Topics

Disease

5Opioid-Induced Constipation
06/2020 - 01/2018
2Cancer Pain
10/2018 - 12/2014
1Chronic Kidney Failure (Chronic Renal Failure)
01/2020
1Neoplasms (Cancer)
10/2018
1Body Weight (Weight, Body)
10/2018
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
10/2018
1Pain (Aches)
12/2014
1Atherosclerosis
07/2013
1Cardiovascular Diseases (Cardiovascular Disease)
07/2013
1Inflammation (Inflammations)
07/2013

Drug/Important Bio-Agent (IBA)

5naldemedineIBA
06/2020 - 01/2018
4Narcotic Antagonists (Opioid Antagonists)IBA
06/2020 - 01/2018
1CreatinineIBA
10/2018
1Opioid Analgesics (Opioids)IBA
01/2018
1Oxycodone (Oxycontin)FDA LinkGeneric
12/2014
1Reactive Oxygen Species (Oxygen Radicals)IBA
07/2013

Therapy/Procedure

1Therapeutics
01/2018